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Detection of Thiopurine S-Methyltransferase (TPMT) Polymorphisms TPMT*3A, TPMT*3B and TPMT*3C in Children with Acute Lymphoblastic Leukemia
Background: Thiopurines are essential medications in Acute Lymphoblastic Leukemia (ALL) treatment protocols as anti-cancer agents since long time; however, their use might result in unexpected toxicities in ALL children due to the low thiopurine S-methyltransferase (TPMT) activity, a major enzyme in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Faculty of Medicine University of Baghdad
2018-12-01
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| Colecção: | مجلة كلية الطب |
| Assuntos: | |
| Acesso em linha: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/608 |
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