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New functions of XPC in the protection of human skin cells from oxidative damage
Xeroderma pigmentosum (XP) C is involved in the recognition of a variety of bulky DNA-distorting lesions in nucleotide excision repair. Here, we show that XPC plays an unexpected and multifaceted role in cell protection from oxidative DNA damage. XP-C primary keratinocytes and fibroblasts are hypers...
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| Hoofdauteurs: | , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1570445/ https://ncbi.nlm.nih.gov/pubmed/16957781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601277 |
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