New functions of XPC in the protection of human skin cells from oxidative damage

Xeroderma pigmentosum (XP) C is involved in the recognition of a variety of bulky DNA-distorting lesions in nucleotide excision repair. Here, we show that XPC plays an unexpected and multifaceted role in cell protection from oxidative DNA damage. XP-C primary keratinocytes and fibroblasts are hypers...

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Bibliografische gegevens
Hoofdauteurs: D'Errico, Mariarosaria, Parlanti, Eleonora, Teson, Massimo, de Jesus, Bruno M Bernardes, Degan, Paolo, Calcagnile, Angelo, Jaruga, Pawel, Bjørås, Magnar, Crescenzi, Marco, Pedrini, Antonia M, Egly, Jean-Marc, Zambruno, Giovanna, Stefanini, Miria, Dizdaroglu, Miral, Dogliotti, Eugenia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570445/
https://ncbi.nlm.nih.gov/pubmed/16957781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601277
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