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Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein

Activation of effector caspases is a final step during apoptosis. Single-cell imaging studies have demonstrated that this process may occur as a rapid, all-or-none response, triggering a complete substrate cleavage within 15 min. Based on biochemical data from HeLa cells, we have developed a computa...

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Hlavní autoři: Rehm, Markus, Huber, Heinrich J, Dussmann, Heiko, Prehn, Jochen H M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570423/
https://ncbi.nlm.nih.gov/pubmed/16932741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601295
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