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Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability
The intrinsic, or mitochondrial, pathway of caspase activation is essential for apoptosis induction by various stimuli including cytotoxic stress. It depends on the cellular context, whether cytochrome c released from mitochondria induces caspase activation gradually or in an all-or-none fashion, an...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1570177/ https://ncbi.nlm.nih.gov/pubmed/16978046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020120 |
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