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Recurrent design patterns in the feedback regulation of the mammalian signalling network

Biochemical networks are characterized by recurrent patterns and motifs, but the design principles underlying the dynamics of the mammalian intracellular signalling network remain unclear. We systematically analysed decay rates of 134 signalling proteins and investigated their gene expression profil...

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Bibliografiske detaljer
Main Authors: Legewie, Stefan, Herzel, Hanspeter, Westerhoff, Hans V, Blüthgen, Nils
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424294/
https://ncbi.nlm.nih.gov/pubmed/18463614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.29
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