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Ultrasensitization: Switch-Like Regulation of Cellular Signaling by Transcriptional Induction

Cellular signaling networks are subject to transcriptional and proteolytic regulation under both physiological and pathological conditions. For example, the expression of proteins subject to covalent modification by phosphorylation is known to be altered upon cellular differentiation or during carci...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Legewie, Stefan, Blüthgen, Nils, Schäfer, Reinhold, Herzel, Hanspeter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1274294/
https://ncbi.nlm.nih.gov/pubmed/16261195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0010054
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