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Competing Docking Interactions can Bring About Bistability in the MAPK Cascade

Mitogen-activated protein kinases are crucial regulators of various cell fate decisions including proliferation, differentiation, and apoptosis. Depending on the cellular context, the Raf-Mek-Erk mitogen-activated protein kinase cascade responds to extracellular stimuli in an all-or-none manner, mos...

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Detalhes bibliográficos
Main Authors: Legewie, Stefan, Schoeberl, Birgit, Blüthgen, Nils, Herzel, Hanspeter
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965452/
https://ncbi.nlm.nih.gov/pubmed/17526574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109132
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