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Competing Docking Interactions can Bring About Bistability in the MAPK Cascade
Mitogen-activated protein kinases are crucial regulators of various cell fate decisions including proliferation, differentiation, and apoptosis. Depending on the cellular context, the Raf-Mek-Erk mitogen-activated protein kinase cascade responds to extracellular stimuli in an all-or-none manner, mos...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biophysical Society
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965452/ https://ncbi.nlm.nih.gov/pubmed/17526574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109132 |
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