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The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference

BACKGROUND: RNA interference (RNAi) has proven to be a powerful tool to suppress gene expression and can be used as a therapeutic strategy against human pathogenic viruses such as human immunodeficiency virus type 1 (HIV-1). Theoretically, RNAi-mediated inhibition can occur at two points in the repl...

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Detalhes bibliográficos
Main Authors: Westerhout, Ellen M, ter Brake, Olivier, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569866/
https://ncbi.nlm.nih.gov/pubmed/16948865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-57
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