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Accumulation of Recessive Lethal Mutations in Saccharomyces cerevisiae mlh1 Mismatch Repair Mutants Is Not Associated With Gross Chromosomal Rearrangements
We examined mismatch repair (MMR)-defective diploid strains of budding yeast grown for ∼160 generations to determine whether decreases in spore viability due to the uncovering of recessive lethal mutations correlated with an increase in gross chromosomal rearrangements (GCRs). No GCRs were detected...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Copyright © 2006 by the Genetics Society of America
2006
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569777/ https://ncbi.nlm.nih.gov/pubmed/16816424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.059311 |
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