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Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2

Mad2 is an essential component of the spindle assembly checkpoint (SAC), a molecular device designed to coordinate anaphase onset with the completion of chromosome attachment to the spindle. Capture of chromosome by microtubules occur on protein scaffolds known as kinetochores. The SAC proteins are...

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Bibliografiske detaljer
Main Authors: DeAntoni, Anna, Sala, Valeria, Musacchio, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569476/
https://ncbi.nlm.nih.gov/pubmed/15897186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2004.1618
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