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Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses

Clinical trials are testing oncolytic viruses (OVs) as therapies for cancer. We have shown that animals that have brain tumors and are treated with a herpes simplex virus (HSV)-derived OV live significantly longer when cyclophosphamide (CPA) is preadministered. Here, we explore the mechanisms behind...

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書誌詳細
主要な著者: Fulci, Giulia, Breymann, Laura, Gianni, Davide, Kurozomi, Kazuhiko, Rhee, Sarah S., Yu, Jianhua, Kaur, Balveen, Louis, David N., Weissleder, Ralph, Caligiuri, Michael A., Chiocca, E. Antonio
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568940/
https://ncbi.nlm.nih.gov/pubmed/16908838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605496103
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