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Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
Clinical trials are testing oncolytic viruses (OVs) as therapies for cancer. We have shown that animals that have brain tumors and are treated with a herpes simplex virus (HSV)-derived OV live significantly longer when cyclophosphamide (CPA) is preadministered. Here, we explore the mechanisms behind...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1568940/ https://ncbi.nlm.nih.gov/pubmed/16908838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605496103 |
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