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A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity
The acute depletion of membrane cholesterol causes the concentration of pERK1/2 in caveola/raft lipid domains and the cytosol of human fibroblasts to dramatically increase. This increase could be caused by either the activation of MEK-1 or the inhibition of a pERK phosphatase. Here we describe the i...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156752/ https://ncbi.nlm.nih.gov/pubmed/12773382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg255 |
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