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A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity

The acute depletion of membrane cholesterol causes the concentration of pERK1/2 in caveola/raft lipid domains and the cytosol of human fibroblasts to dramatically increase. This increase could be caused by either the activation of MEK-1 or the inhibition of a pERK phosphatase. Here we describe the i...

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Bibliografiske detaljer
Main Authors: Wang, Ping-yuan, Liu, Pingsheng, Weng, Jian, Sontag, Estelle, Anderson, Richard G.W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156752/
https://ncbi.nlm.nih.gov/pubmed/12773382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg255
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