Genotyping single nucleotide polymorphisms directly from genomic DNA by invasive cleavage reaction on microspheres
Here we report proof-of-principle for a microsphere-based genotyping assay that detects single nucleotide polymorphisms (SNPs) directly from human genomic DNA samples. This assay is based on a structure-specific cleavage reaction that achieves single base discrimination with a 5′-nuclease which reco...
Збережено в:
| Опубліковано в:: | Nucleic Acids Res |
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| Автори: | , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Oxford University Press
2003
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156743/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12771230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng066 |
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