Genotyping single nucleotide polymorphisms directly from genomic DNA by invasive cleavage reaction on microspheres

Here we report proof-of-principle for a microsphere-based genotyping assay that detects single nucleotide polymorphisms (SNPs) directly from human genomic DNA samples. This assay is based on a structure-specific cleavage reaction that achieves single base discrimination with a 5′-nuclease which reco...

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Hlavní autoři: Rao, Kakuturu V. N., Stevens, Priscilla Wilkins, Hall, Jeff G., Lyamichev, Victor, Neri, Bruce P., Kelso, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
NAR Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC156743/
https://ncbi.nlm.nih.gov/pubmed/12771230
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