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The effect of deep pore mutations on the action of phenylalkylamines on the Kv1.3 potassium channel
1. We investigated the action of the phenylalkylamines verapamil and N-methyl-verapamil on the Kv1.3 potassium channel using the whole-cell configuration of the patch-clamp technique. Our goal was to identify their binding as a prerequisite for using the phenylalkylamines as small, well-defined mole...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1999
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566106/ https://ncbi.nlm.nih.gov/pubmed/10455250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702599 |
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