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Observation of σ-pore currents in mutant hKv1.2_V370C potassium channels
Current through the σ-pore was first detected in hKv1.3_V388C channels, where the V388C mutation in hKv1.3 channels opened a new pathway (σ-pore) behind the central α-pore. Typical for this mutant channel was inward current at potentials more negative than -100 mV when the central α-pore was closed....
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398642/ https://ncbi.nlm.nih.gov/pubmed/28426823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176078 |
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