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A single amino acid confers barbiturate sensitivity upon the GABA ρ(1) receptor
Many structurally diverse general anaesthetics enhance inhibitory neurotransmission in the central nervous system by interacting with the GABA(A) receptor. By contrast, GABA receptors composed of the ρ(1) subunit are anaesthetic-insensitive. Here, we demonstrate that both δ-hexachlorocyclohexane (δ-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566072/ https://ncbi.nlm.nih.gov/pubmed/10401548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702611 |
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