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JTT-608 restores impaired early insulin secretion in diabetic Goto-Kakizaki rats
1. We investigated the pharmacological effects of a new antidiabetic agent, JTT-608, in comparison with the sulphonylurea tolbutamide, in Goto-Kakizaki (GK) rats, a genetic model of non-obese insulin-dependent diabetes mellitus (NIDDM). 2. In isolated perfused pancreas from GK rats, JTT-608 (200 μM)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565945/ https://ncbi.nlm.nih.gov/pubmed/10323602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702481 |
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