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Saxagliptin Restores Vascular Mitochondrial Exercise Response in the Goto-Kakizaki Rat
Cardiovascular disease risk and all-cause mortality are largely predicted by physical fitness. Exercise stimulates vascular mitochondrial biogenesis through endothelial nitric oxide synthase (eNOS), sirtuins, and PPARγ coactivator 1α (PGC-1α), a response absent in diabetes and hypertension. We hypot...
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| 出版年: | J Cardiovasc Pharmacol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Journal of Cardiovascular Pharmacology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320657/ https://ncbi.nlm.nih.gov/pubmed/25264749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000170 |
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