Modulation of the gating of ClC-1 by S-(–) 2-(4-chlorophenoxy) propionic acid

1. Using whole-cell patch-clamping and Sf-9 cells expressing the rat skeletal muscle chloride channel, rClC-1, the cellular mechanism responsible for the myotonic side effects of clofibrate derivatives was examined. 2. RS-(±) 2-(4-chlorophenoxy)propionic acid (RS-(±) CPP) and its S-(−) enantiomer pr...

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Main Authors: Aromataris, E C, Astill, D St J, Rychkov, G Y, Bryant, S H, Bretag, A H, Roberts, M L
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565926/
https://ncbi.nlm.nih.gov/pubmed/10217531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702459
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