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Modulation of the gating of ClC-1 by S-(–) 2-(4-chlorophenoxy) propionic acid
1. Using whole-cell patch-clamping and Sf-9 cells expressing the rat skeletal muscle chloride channel, rClC-1, the cellular mechanism responsible for the myotonic side effects of clofibrate derivatives was examined. 2. RS-(±) 2-(4-chlorophenoxy)propionic acid (RS-(±) CPP) and its S-(−) enantiomer pr...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565926/ https://ncbi.nlm.nih.gov/pubmed/10217531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702459 |
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