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Non-specific action of methoxamine on I(to), and the cloned channels hKv 1.5 and Kv 4.2
1. The α(1)-adrenoceptor agonist methoxamine acted independently of receptor activation to reduce I(to) and the sustained outward current in rat ventricular myocytes, and hKv 1.5 and Kv 4.2 cloned K(+) channel currents. Two hundred μM methoxamine reduced I(to) by 36% in the presence of 2 μM prazosin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565843/ https://ncbi.nlm.nih.gov/pubmed/10188969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702335 |
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