Loading...

Inhibition of ornithine decarboxylase potentiates nitric oxide production in LPS-activated J774 cells

1. We have examined whether modulation of the polyamine biosynthetic pathway, through inhibition by α-difluoromethylornithine (DFMO) of the rate limiting enzyme, ornithine decarboxylase (ODC), modulates NO synthesis in J774 macrophages. 2. DFMO potentiated LPS-stimulated nitrite production in both a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Baydoun, Anwar R, Morgan, David M L
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565739/
https://ncbi.nlm.nih.gov/pubmed/9884080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702231
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!