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Leptin potentiates IFN-γ-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1

1. Leptin, a pleiotropic hormone believed to regulate body weight, has recently been associated with inflammatory states and immune activity. Here we have studied the effect of leptin on expression of IFN-γ-induced nitric oxide synthase (iNOS) and cyclo-oxygenase-2 (COX-2), both prominent markers of...

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Detalhes bibliográficos
Main Authors: Raso, Giuseppina Mattace, Pacilio, Maria, Esposito, Emanuela, Coppola, Anna, Di Carlo, Raffaele, Meli, Rosaria
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573547/
https://ncbi.nlm.nih.gov/pubmed/12411410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704903
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