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Mg(2+) and ATP dependence of K(ATP) channel modulator binding to the recombinant sulphonylurea receptor, SUR2B

1. The binding of modulators of the ATP-sensitive K(+) channel (K(ATP) channel) to the murine sulphonylurea receptor, SUR2B, was investigated. SUR2B, a proposed subunit of the vascular K(ATP) channel, was expressed in HEK 293 cells and binding assays were performed in membranes at 37°C using the tri...

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Detalles Bibliográficos
Main Authors: Hambrock, Annette, Löffler-Walz, Cornelia, Kurachi, Yoshihisa, Quast, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565653/
https://ncbi.nlm.nih.gov/pubmed/9806343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702109
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