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Hepatic structure-pharmacokinetic relationships: The hepatic disposition and metabolite kinetics of a homologous series of O-acyl derivatives of salicylic acid

1. The hepatic disposition and metabolite kinetics of a homologous series of O-acyl (acetyl, propionyl, butanoyl, pentanoyl, hexanoyl and octanoyl) esters of salicylic acid (C2SA, C3SA, C4SA, C5SA, C6SA and C8SA, respectively) was determined using a single-pass, in-situ rat liver preparation. 2. The...

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Bibliografiske detaljer
Main Authors: Hung, Daniel Y, Mellick, George D, Anissimov, Yuri G, Weiss, Michael, Roberts, Michael S
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565521/
https://ncbi.nlm.nih.gov/pubmed/9723961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701961
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