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Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver

1. The disposition kinetics of [(3)H]taurocholate ([(3)H]TC) in perfused normal and cholestatic rat livers were studied using the multiple indicator dilution technique and several physiologically based pharmacokinetic models. 2. The serum biochemistry levels, the outflow profiles and biliary recover...

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Autors principals: Hung, Daniel Y, Siebert, Gerhard A, Chang, Ping, Roberts, Michael S
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576117/
https://ncbi.nlm.nih.gov/pubmed/15711588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706148
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