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Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver
1. The disposition kinetics of [(3)H]taurocholate ([(3)H]TC) in perfused normal and cholestatic rat livers were studied using the multiple indicator dilution technique and several physiologically based pharmacokinetic models. 2. The serum biochemistry levels, the outflow profiles and biliary recover...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576117/ https://ncbi.nlm.nih.gov/pubmed/15711588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706148 |
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