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Cytoplasmic binding and disposition kinetics of diclofenac in the isolated perfused rat liver
1. The binding kinetics of diclofenac to hepatocellular structures were evaluated in the perfused rat liver using the multiple indicator dilution technique and a stochastic model of organ transit time density. 2. The single-pass, in situ rat liver preparation was perfused with buffer solution (conta...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572206/ https://ncbi.nlm.nih.gov/pubmed/10903973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703448 |
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