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Competitive and selective antagonism of P2Y(1) receptors by N(6)-methyl 2′-deoxyadenosine 3′,5′-bisphosphate

The antagonist activity of N(6)-methyl 2′-deoxyadenosine 3′,5′-bisphosphate (N6MABP) has been examined at the phospholipase C-coupled P2Y(1) receptor of turkey erythrocyte membranes. N6MABP antagonized 2MeSATP-stimulated inositol phosphate hydrolysis with a potency approximately 20 fold greater than...

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Detalhes bibliográficos
Main Authors: Boyer, José L, Mohanram, Arvind, Camaioni, Emidio, Jacobson, Kenneth A, Harden, T Kendall
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565379/
https://ncbi.nlm.nih.gov/pubmed/9630335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701837
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