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Characterization of [(125)I]-PD164333, an ET(A) selective non-peptide radiolabelled antagonist, in normal and diseased human tissues
1. We have synthesized a new low molecular weight, non-peptide radioligand, [(125)I]-PD164333, an analogue of the orally active butenolide antagonists of the endothelin ET(A) receptor. 2. Analysis of saturation binding assays demonstrated that [(125)I]-PD164333 bound with high affinity to a single p...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
1998
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565157/ https://ncbi.nlm.nih.gov/pubmed/9489609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701597 |
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