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Vasoconstrictor activity of novel endothelin peptide, ET-1((1 – 31)), in human mammary and coronary arteries in vitro

1. The ability of the putative chymase product of big endothelin-1 (big ET-1), ET-1((1 – 31)), to constrict isolated endothelium-denuded preparations of human coronary and internal mammary artery was determined. 2. pD(2) values in coronary and mammary artery respectively were 8.21±0.12 (n=14) and 8....

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Detalhes bibliográficos
Main Authors: Maguire, Janet J, Kuc, Rhoda E, Davenport, Anthony P
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573069/
https://ncbi.nlm.nih.gov/pubmed/11704658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704384
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