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Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1

1. We have determined the distribution of receptors for human urotensin-II (U-II) in human and rat CNS and peripheral tissues. 2. In rat, [(125)I]-U-II binding density was highest in the abducens nucleus of brainstem (139.6±14 amol mm(−2)). Moderate levels were detected in dorsal horn of spinal cord...

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Detalhes bibliográficos
Main Authors: Maguire, Janet J, Kuc, Rhoda E, Davenport, Anthony P
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572358/
https://ncbi.nlm.nih.gov/pubmed/11015293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703601
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