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Is urotensin-II the new endothelin?

Urotensin-II (U-II), a peptide isolated from the urophysis of teleost fish 35 years ago, is the endogenous ligand of the mammalian orphan receptor GPR14/SENR. Recently, human homologues of both the receptor (UT-II) and the peptide (hU-II) have been discovered. Following de-orphanization, hU-II was d...

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Detalhes bibliográficos
Main Authors: Maguire, Janet J, Davenport, Anthony P
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573544/
https://ncbi.nlm.nih.gov/pubmed/12381671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704924
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