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Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors

The metabotropic glutamate receptors (mGluRs) within the Family C subclass of G protein-coupled receptors are crucial modulators of synaptic transmission. However, their closest relatives include a diverse group of sensory receptors whose biological functions are not associated with neurotransmissio...

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Detalhes bibliográficos
Main Authors: Kuang, Donghui, Yao, Yi, MacLean, David, Wang, Minghua, Hampson, David R., Chang, Belinda S. W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563994/
https://ncbi.nlm.nih.gov/pubmed/16966606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604717103
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