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Quantification of Ligand Binding to G-Protein Coupled Receptors on Cell Membranes by Ellipsometry
G-protein-coupled receptors (GPCRs) are prime drug targets and targeted by approximately 60% of current therapeutic drugs such as β-blockers, antipsychotics and analgesics. However, no biophysical methods are available to quantify their interactions with ligand binding in a native environment. Here,...
Tallennettuna:
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458955/ https://ncbi.nlm.nih.gov/pubmed/23049983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046221 |
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