Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

Hepatitis C virus (HCV) cell entry involves interaction between the viral envelope glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 determinants important for successful binding will facilitate development of entry inhibitors designed to block this interaction. Previous...

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Bibliographic Details
Main Authors: Owsianka, Ania M., Timms, Judith M., Tarr, Alexander W., Brown, Richard J. P., Hickling, Timothy P., Szwejk, Aleksandra, Bienkowska-Szewczyk, Krystyna, Thomson, Brian J., Patel, Arvind H., Ball, Jonathan K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563869/
https://ncbi.nlm.nih.gov/pubmed/16912317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00271-06
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