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Identification of Conserved Residues in Hepatitis C Virus Envelope Glycoprotein E2 That Modulate Virus Dependence on CD81 and SRB1 Entry Factors

In spite of the high variability of its sequence, hepatitis C virus (HCV) envelope glycoprotein E2 contains several conserved regions. In this study, we explored the structural and functional features of the highly conserved E2 segment from amino acid (aa) 502 to 520, which had been proposed as a fu...

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Détails bibliographiques
Auteurs principaux: Lavie, Muriel, Sarrazin, Stéphane, Montserret, Roland, Descamps, Véronique, Baumert, Thomas F., Duverlie, Gilles, Séron, Karin, Penin, François, Dubuisson, Jean
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178871/
https://ncbi.nlm.nih.gov/pubmed/24990994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01402-14
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