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Identification of Conserved Residues in Hepatitis C Virus Envelope Glycoprotein E2 That Modulate Virus Dependence on CD81 and SRB1 Entry Factors

In spite of the high variability of its sequence, hepatitis C virus (HCV) envelope glycoprotein E2 contains several conserved regions. In this study, we explored the structural and functional features of the highly conserved E2 segment from amino acid (aa) 502 to 520, which had been proposed as a fu...

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Detalhes bibliográficos
Main Authors: Lavie, Muriel, Sarrazin, Stéphane, Montserret, Roland, Descamps, Véronique, Baumert, Thomas F., Duverlie, Gilles, Séron, Karin, Penin, François, Dubuisson, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178871/
https://ncbi.nlm.nih.gov/pubmed/24990994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01402-14
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