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Identification of Conserved Residues in Hepatitis C Virus Envelope Glycoprotein E2 That Modulate Virus Dependence on CD81 and SRB1 Entry Factors

In spite of the high variability of its sequence, hepatitis C virus (HCV) envelope glycoprotein E2 contains several conserved regions. In this study, we explored the structural and functional features of the highly conserved E2 segment from amino acid (aa) 502 to 520, which had been proposed as a fu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lavie, Muriel, Sarrazin, Stéphane, Montserret, Roland, Descamps, Véronique, Baumert, Thomas F., Duverlie, Gilles, Séron, Karin, Penin, François, Dubuisson, Jean
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178871/
https://ncbi.nlm.nih.gov/pubmed/24990994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01402-14
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