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Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

Hepatitis C virus (HCV) cell entry involves interaction between the viral envelope glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 determinants important for successful binding will facilitate development of entry inhibitors designed to block this interaction. Previous...

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Main Authors:	Owsianka, Ania M., Timms, Judith M., Tarr, Alexander W., Brown, Richard J. P., Hickling, Timothy P., Szwejk, Aleksandra, Bienkowska-Szewczyk, Krystyna, Thomson, Brian J., Patel, Arvind H., Ball, Jonathan K.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology 2006
נושאים:	Virus-Cell Interactions
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1563869/ https://ncbi.nlm.nih.gov/pubmed/16912317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00271-06
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Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

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