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Catechol O-methyltransferase val(158)-met genotype and individual variation in the brain response to amphetamine

Monamines subserve many critical roles in the brain, and monoaminergic drugs such as amphetamine have a long history in the treatment of neuropsychiatric disorders and also as a substance of abuse. The clinical effects of amphetamine are quite variable, from positive effects on mood and cognition in...

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Autori principali: Mattay, Venkata S., Goldberg, Terry E., Fera, Francesco, Hariri, Ahmad R., Tessitore, Alessandro, Egan, Michael F., Kolachana, Bhaskar, Callicott, Joseph H., Weinberger, Daniel R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC156347/
https://ncbi.nlm.nih.gov/pubmed/12716966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0931309100
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