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DNA synthesis by a polymerase provides the driving force to accelerate DNA unwinding by a helicase
Helicases are molecular motors that use the energy of NTP hydrolysis to translocate along a nucleic acid strand and catalyze reactions such as DNA unwinding. The ring-shaped helicase1 of bacteriophage T7 translocates along single stranded (ss) DNA at a speed of 130 base per second2. However, T7 heli...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563444/ https://ncbi.nlm.nih.gov/pubmed/15902262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03615 |
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