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Polymerase θ-helicase efficiently unwinds DNA and RNA-DNA hybrids
POLQ is a unique multifunctional replication and repair gene that encodes for a N-terminal superfamily 2 helicase and a C-terminal A-family polymerase. Although the function of the polymerase domain has been investigated, little is understood regarding the helicase domain. Multiple studies have repo...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892577/ https://ncbi.nlm.nih.gov/pubmed/29444826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000565 |
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