NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

Parkinson's disease (PD) is a neurodegenerative disorder of uncertain pathogenesis characterized by a loss of substantia nigra pars compacta (SNpc) dopaminergic (DA) neurons, and can be modeled by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Both inflammatory processes and oxi...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Wu, Du-Chu, Teismann, Peter, Tieu, Kim, Vila, Miquel, Jackson-Lewis, Vernice, Ischiropoulos, Harry, Przedborski, Serge
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2003
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12721370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0937239100
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