Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

The organic cation transporter, OCT1, is a major hepatic transporter that mediates the uptake of many organic cations from the blood into the liver where the compounds may be metabolized or secreted into the bile. Because OCT1 interacts with a variety of structurally diverse organic cations, includi...

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Bibliografiska uppgifter
Huvudupphovsmän: Shu, Yan, Leabman, Maya K., Feng, Bo, Mangravite, Lara M., Huang, Conrad C., Stryke, Doug, Kawamoto, Michiko, Johns, Susan J., DeYoung, Joseph, Carlson, Elaine, Ferrin, Thomas E., Herskowitz, Ira, Giacomini, Kathleen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC156299/
https://ncbi.nlm.nih.gov/pubmed/12719534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730858100
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