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Molecular Origins for the Dominant Negative Function of Human Glucocorticoid Receptor Beta
This study molecularly elucidates the basis for the dominant negative mechanism of the glucocorticoid receptor (GR) isoform hGRβ, whose overexpression is associated with human glucocorticoid resistance. Using a series of truncated hGRα mutants and sequential mutagenesis to generate a series of hGRα/...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156139/ https://ncbi.nlm.nih.gov/pubmed/12773573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4319-4330.2003 |
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