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Human Glucocorticoid Receptor β Binds RU-486 and Is Transcriptionally Active

Human glucocorticoid receptor (hGR) is expressed as two alternately spliced C-terminal isoforms, α and β. In contrast to the canonical hGRα, hGRβ is a nucleus-localized orphan receptor thought not to bind ligand and not to affect gene transcription other than by acting as a dominant negative to hGRα...

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Detalhes bibliográficos
Main Authors: Lewis-Tuffin, Laura J., Jewell, Christine M., Bienstock, Rachelle J., Collins, Jennifer B., Cidlowski, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820503/
https://ncbi.nlm.nih.gov/pubmed/17242213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01439-06
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