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Human Glucocorticoid Receptor β Binds RU-486 and Is Transcriptionally Active
Human glucocorticoid receptor (hGR) is expressed as two alternately spliced C-terminal isoforms, α and β. In contrast to the canonical hGRα, hGRβ is a nucleus-localized orphan receptor thought not to bind ligand and not to affect gene transcription other than by acting as a dominant negative to hGRα...
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Autors principals: | , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Society for Microbiology
2007
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820503/ https://ncbi.nlm.nih.gov/pubmed/17242213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01439-06 |
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