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Molecular Origins for the Dominant Negative Function of Human Glucocorticoid Receptor Beta
This study molecularly elucidates the basis for the dominant negative mechanism of the glucocorticoid receptor (GR) isoform hGRβ, whose overexpression is associated with human glucocorticoid resistance. Using a series of truncated hGRα mutants and sequential mutagenesis to generate a series of hGRα/...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2003
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156139/ https://ncbi.nlm.nih.gov/pubmed/12773573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4319-4330.2003 |
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