Methylation of Adjacent CpG Sites Affects Sp1/Sp3 Binding and Activity in the p21(Cip1) Promoter

DNA methylation in the promoter of certain genes is associated with transcriptional silencing. Methylation affects gene expression directly by interfering with transcription factor binding and/or indirectly by recruiting histone deacetylases through methyl-DNA-binding proteins. In this study, we dem...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Zhu, Wei-Guo, Srinivasan, Kanur, Dai, Zunyan, Duan, Wenrui, Druhan, Lawrence J., Ding, Haiming, Yee, Lisa, Villalona-Calero, Miguel A., Plass, Christoph, Otterson, Gregory A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2003
Θέματα:	Transcriptional Regulation
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12773551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.12.4056-4065.2003
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